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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPTY2D1
All Species:
17.58
Human Site:
S422
Identified Species:
32.22
UniProt:
Q68D10
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68D10
NP_919261.2
685
75546
S422
S
K
K
P
T
N
D
S
N
P
S
R
R
T
V
Chimpanzee
Pan troglodytes
XP_508321
684
75407
S422
S
K
K
P
T
N
D
S
N
P
S
R
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001082108
684
75599
S422
S
K
K
P
T
N
D
S
N
P
S
R
R
T
V
Dog
Lupus familis
XP_534086
793
86791
L533
T
K
K
P
A
S
D
L
N
L
S
R
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q68FG3
682
74799
S422
I
R
K
L
A
S
N
S
H
L
S
G
R
T
L
Rat
Rattus norvegicus
XP_002725626
681
74519
S422
I
R
K
P
A
S
N
S
H
P
S
G
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517926
644
69600
P380
S
Q
P
S
H
S
R
P
G
P
S
P
H
N
G
Chicken
Gallus gallus
XP_421015
633
66869
R377
E
T
N
S
S
A
K
R
P
S
S
S
L
G
K
Frog
Xenopus laevis
Q6NU13
800
83727
S531
A
G
V
S
G
S
V
S
S
F
A
R
P
R
S
Zebra Danio
Brachydanio rerio
Q6DGN6
629
69420
G384
P
H
K
N
S
A
H
G
R
P
S
N
F
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8IMP6
581
65683
K343
A
P
S
D
S
F
K
K
P
T
A
P
Q
P
T
Honey Bee
Apis mellifera
XP_395689
579
67372
N341
N
K
I
Q
D
N
R
N
N
T
N
C
S
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793115
639
72247
A375
E
S
R
P
D
S
R
A
V
P
G
K
S
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
96.7
73.6
N.A.
80.5
82.1
N.A.
55.6
47.8
43
42.7
N.A.
28.3
23.2
N.A.
24
Protein Similarity:
100
99.5
98.5
78.8
N.A.
89.9
90.3
N.A.
66.5
58
56.6
58.6
N.A.
44.2
41.6
N.A.
39.8
P-Site Identity:
100
100
100
60
N.A.
33.3
46.6
N.A.
20
6.6
13.3
20
N.A.
0
20
N.A.
13.3
P-Site Similarity:
100
100
100
80
N.A.
66.6
80
N.A.
33.3
13.3
40
33.3
N.A.
26.6
40
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
24
16
0
8
0
0
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
8
16
0
31
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
8
0
0
8
8
0
% F
% Gly:
0
8
0
0
8
0
0
8
8
0
8
16
0
8
8
% G
% His:
0
8
0
0
8
0
8
0
16
0
0
0
8
0
0
% H
% Ile:
16
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
39
54
0
0
0
16
8
0
0
0
8
0
0
16
% K
% Leu:
0
0
0
8
0
0
0
8
0
16
0
0
8
0
24
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
8
0
31
16
8
39
0
8
8
0
16
0
% N
% Pro:
8
8
8
47
0
0
0
8
16
54
0
16
8
8
0
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
16
8
0
0
0
24
8
8
0
0
39
47
8
8
% R
% Ser:
31
8
8
24
24
47
0
47
8
8
70
8
16
8
8
% S
% Thr:
8
8
0
0
24
0
0
0
0
16
0
0
0
47
16
% T
% Val:
0
0
8
0
0
0
8
0
8
0
0
0
0
0
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _